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Synthetic description of the product:Mizoribine (INN, trade name Bredinin) is an immunosuppressive drug. The compound was first observed in Tokyo, Japan, in 1971.[1] It is a natural product, first isolated from the mould Eupenicillium brefeldianum. Mizoribine (MZB) is an imidazole nucleoside that has been used in renal transplantation, and in steroid-resistant nephrotic syndrome, IgA nephropathy, lupus, as well as for adults with rheumatoid arthritis, lupus nephritis and other rheumatic diseases. MZB exerts its activity through selective inhibition of inosine monophosphate synthetase and guanosine monophosphate synthetase, resulting in the complete inhibition of guanine nucleotide synthesis without incorporation into nucleotides. It arrests DNA synthesis in the S phase of cellular division. Thus, MZB has less toxicity than azathioprine, another immunosuppressant used for some of the same diseases.

Product Name: Mizoribine

Structural formula
 
Synonyms:Bredinin
chemical name:5-hydroxy-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide
CAS:50924-49-7;50524-49-7
Molecular Formula:C9H13N3O6
Molecular Weight:259.216
 

                   PRODUCT SPECIFICATIONS             ||                          DATA PROCESS SUMMARY

Appearance
  drying shrinkage  
Assay   Water  
impurity      
heavy metal      
Residue on ignition      
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   MAIN RAW MATERIAL for FERMENTATION    ||             MAIN RAW MATERIAL for RECOVERY

quality standard
  packing specification  
product certification   Outside the bag material  
quality guarantee period   Other  
       
 
 
DSP – BLOCK DIAGRAM 

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