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Synthetic description of the product:
Ascomycin, also called Immunomycin, FR-900520, FK520, is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties. It can be used to treat autoimmune diseases and skin diseases, and can help prevent rejection after an organ transplant.Ascomycin acts by binding to immunophilins, especially macrophilin-12. It appears that Ascomycin inhibits the production of Th1 (interferon- and IL-2) and Th2 (IL-4 and IL-10) cytokines. Additionally, ascomycin preferentially inhibits the activation of mast cells, an important cellular component of the atopic response. Ascomycin produces a more selective immunomodulatory effect in that it inhibits the elicitation phase of allergic contact dermatitis but does not impair the primary immune response when administered systemically.Ascomycin is produced by the fermentation of Streptomyces hygroscopicus.

Product Name: Ascomycin

Structural formula
Synonyms:AAG; FK-520; FR-900520
chemical name:(3S,4R,5S,8R,12S,14R,15R,16S,18R,19R,26aS)-8-ethyl-5,19-dihydroxy-3-{(E)-2-[(1S,3R,4S)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl}-14,16-dimethoxy-4,10,12,18-tetramethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone
CAS:104987-12-4;11011-38-4
Molecular Formula:C43H67NO12
Molecular Weight:789.99
 

                   PRODUCT SPECIFICATIONS             ||                          DATA PROCESS SUMMARY

Appearance
  drying shrinkage  
Assay   Water  
impurity      
heavy metal      
Residue on ignition      
Content      
 
 
   MAIN RAW MATERIAL for FERMENTATION    ||             MAIN RAW MATERIAL for RECOVERY

quality standard
  packing specification  
product certification   Outside the bag material  
quality guarantee period   Other  
       
 
 
DSP – BLOCK DIAGRAM 

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